Southwest Ohio Vacation Packages 2026 from $351

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Your Southwest Ohio Vacation

When you book a Southwest Ohio vacation package, you can leave the travel details to us and concentrate on enjoying your escape. Whether it's the distilleries and craft breweries and dining, or the countless other highlights you're coming to see, this destination has plenty to offer. With so much to see on a trip to Southwest Ohio, it can be hard to know where to begin. Kick off your journey in Cincinnati at Great American Ball Park and Paycor Stadium — two much-loved attractions here. Another top city worthy of a spot on your itinerary is Dayton. Don't miss National Museum of the United States Air Force and Dayton Mall Shopping Center. Expedia has hotels, flights, car rentals and more to help you organize your own tailored Southwest Ohio vacation today.

The Latest Southwest Ohio vacation packages

Price found within the past 48 hours. Click for updated prices.

Belterra Casino Resort

$351

per person

Nov 25 - Nov 28

found 16 hours ago

Roundtrip flight included

Orlando (MCO) to Cincinnati (CVG)

8.6/10 Excellent! (1,006 reviews)

21c Museum Hotel Cincinnati

Downtown Cincinnati

$389

per person

Nov 25 - Nov 28

found 20 hours ago

Roundtrip flight included

Orlando (MCO) to Cincinnati (CVG)

8.6/10 Excellent! (1,006 reviews)

Jungle House Boutique Residences – Downtown Columbus & Short North

Downtown Columbus

Save 100% on your flight

$1,700

per person

Nov 6 - Nov 9

found 1 day ago

Roundtrip flight included

Boston (BOS) to Columbus (CMH)

10/10 Exceptional! (24 reviews)

Jungle House Urban Lofts – Arena District & Short North

Downtown Columbus

Save 100% on your flight

$1,204

per person

Nov 6 - Nov 9

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Columbus (CMH)

9.8/10 Exceptional! (27 reviews)

Clean and comfortable and in a great location to visit restaurants and shops in Short North. Very spacious and convenient with quirky jungle themed fun!

Reviewed on Sep 2, 2026

Jungle House Downtown Columbus – Modern Boutique Suites

Downtown Columbus

$1,391

per person

Nov 6 - Nov 9

found 1 day ago

Roundtrip flight included

Boston (BOS) to Columbus (CMH)

10/10 Exceptional! (28 reviews)

Great place to stay right in down town Absolutely stunning

Reviewed on Aug 25, 2026

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Where to stay in Southwest Ohio

Find the best Southwest Ohio areas and neighborhoods for the activities you enjoy most. Learn more about Southwest Ohio

A bronze statue of a child on a fountain with water spouting from the top.

Downtown Cincinnati

3 out of top 10 points of interest in this area

Discover historic architecture and districts in the heart of the city, with museums like the Contemporary Arts Center and National Underground Railroad Freedom Center. Enjoy waterfront dining at The Banks, and take in the views from Carew Tower's observation deck.

Over-the-Rhine

Boasting a rich architectural heritage, Over-the-Rhine offers a vibrant food scene with local chefs and artisan brewers. Explore Findlay Market, Cincinnati Music Hall, and Washington Park for a memorable experience.

A park with a pond, rocks, and flowering trees.

Hyde Park

Situated between Interstate 71 and the Ohio River, this neighborhood boasts Hyde Park Square, a hub for family-owned shops, boutiques, and restaurants. Don't miss the Kilgour Fountain and the iconic Graeter's Ice Cream parlor.

A stone bridge with a metal railing, surrounded by autumn trees and a grassy area.

Mount Adams

Surrounded by Eden Park, this residential area boasts landmarks like the Cincinnati Art Museum and Playhouse in the Park. Dine at the converted Rookwood Pottery restaurant and explore historic churches.

A large yellow building with red trim and multiple chimneys, surrounded by a well-maintained lawn and a staircase leading up to the entrance.

Mount Auburn

If you're looking for some top things to see and do in Mount Auburn and surrounding area, you can visit Great American Ball Park and Paycor Stadium.

Stay near popular Southwest Ohio attractions

Great American Ball Park

9.0/10 (1,531 reviews)

Catch an event at Great American Ball Park during your trip to Cincinnati. Amble around the area's riverfront or attend a baseball game.

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A wooden sign with a roller coaster and a large, colorful snake illustration.

Kings Island

9.2/10 (1,397 reviews)

This award-winning amusement and water park in Mason has more than 80 thrilling rides and attractions.

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A large stadium surrounded by urban buildings and roads.

Paycor Stadium

8.6/10 (1,365 reviews)

Catch an event at Paycor Stadium during your trip to Cincinnati. Experience the area's fascinating museums and acclaimed art scene.

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A person taking a photo of a city skyline at sunset.

University of Cincinnati

8.4/10 (1,802 reviews)

Take a campus tour or just explore the area of University of Cincinnati, during your trip to Cincinnati. Experience the area's acclaimed theater scene and great live music.

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A plate of Belgian waffles with butter and powdered sugar.

University of Dayton

8.8/10 (788 reviews)

Enjoy the collegiate vibe when you visit University of Dayton, during your trip to Dayton. Discover the area's lively bars and its fascinating museums.

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A large USAF jet on display with the United States Air Force Museum in the background.

National Museum of the United States Air Force

9.6/10 (1,235 reviews)

From a replica of the Wright brothers’ original plane to high-tech stealth bombers, there are hundreds of unique aircraft to explore at this museum in Dayton, Ohio.

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The entrance to the Cincinnati Zoo & Botanical Garden with a sign above the gate and a flower bed in the foreground.

Cincinnati Zoo and Botanical Garden

9.0/10 (1,727 reviews)

See newborn baby gorillas and tigers at this park dubbed “the Sexiest Zoo in America” thanks to its successful breeding program.

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Hard Rock Casino Cincinnati

8.4/10 (1,405 reviews)

Why not try your luck with a visit to Hard Rock Casino Cincinnati during your visit to Cincinnati? Experience the fascinating museums and acclaimed art scene in this vibrant area.

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What to do in Southwest Ohio

The Escape Game: Epic 60-Minute Adventures at Crocker Park

$42

per adult

See all activities in Southwest Ohio

Southwest Ohio Hotel Deals

Hilton Cincinnati Netherland Plaza

35 W 5th St Cincinnati OH

Fully refundableReserve now, pay when you stay

$127 nightly

$152 total

Sep 27 - Sep 28

Total with taxes and fees

Quality Inn & Suites Florence - Cincinnati South

30 Cavalier Court Florence KY

Fully refundable

$61 nightly

$69 total

Oct 11 - Oct 12

Total with taxes and fees

7.2/10 Good! (1,002 reviews)

"Don't get me wrong, giving 5 stars does NOT mean this is a 5 star hotel. It is probably a 3 star hotel, that warrants a 5 star rating in it's class. The room was clean, the beds & pillows comfy, the breakfast adequate. It's a great price, with 100 times better than you'd expect for the price."

Reviewed on Sep 19, 2026

Radisson Hotel Cincinnati Riverfront

668 W 5th St Covington KY

Fully refundable

$88 nightly

$99 total

Oct 18 - Oct 19

Total with taxes and fees

7.2/10 Good! (3,112 reviews)

"Booked a room almost 2 months in advance. Recieved a cancelation notice less than a week before my stay. No phone call or explanation just a casual email- you're room has been canceled. After calling the property I was directed to leave a message for Savanna as the front desk had been instructed ..."

Reviewed on Sep 20, 2026

See all 3,409 properties in Southwest Ohio

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.